e-MutPath: Computational modelling reveals the functional landscape of genetic mutations rewiring interactome networks
Yongsheng Li, Brandon Burgman, Ishaani S. Khatri, Sairahul R. Pentaparthi, Zhe Su, Daniel James McGrail, Yang Li, Erxi Wu, S. Gail Eckhardt, Nidhi Sahni, S. Stephen Yi
e-MutPath identifies edgetic mutations that perturb functional pathways, revealing cancer vulnerability genes and drug targets through network-based analysis.
Nucleic Acids Research · Oct 20, 2020Peer-reviewedSystems Biology