Modeling the Orthosteric Binding Site of the G Protein-Coupled Odorant Receptor OR5K1
Alessandro Nicoli, Franziska Haag, Patrick Marcinek, Ruiming He, Johanna Kreißl, Jörg Stein, Alessandro Marchetto, Andreas Dunkel, Thomas Frank Hofmann, Dietmar Krautwurst, Antonella Di Pizio
The paper models the orthosteric binding site of the odorant receptor OR5K1 using AI-driven structural data and mutagenesis data to refine ligand binding modes.
Journal of Chemical Information and Modeling · Jan 25, 2023Peer-reviewedMolecular Biology