Differential dynamics specify MeCP2 function at methylated DNA and nucleosomes
G. N. L. Chua, J. W. Watters, P. D. B. Olinares, J. A. Luo, B. T. Chait, S. Liu
This study investigates how MeCP2 interacts with methylated DNA and nucleosomes, revealing distinct dynamics that influence its function in gene repression and Rett syndrome.
bioRxiv · Jun 2, 2023Biophysics