Model biomolecular condensates have heterogeneous structure quantitatively dependent on the interaction profile of their constituent macromolecules
J. C. Shillcock, C. Lagisquet, J. Alexandre, L. Vuillon, J. H. Ipsen
The paper uses simulations to show that model intrinsically-disordered proteins form heterogeneous, structured condensates whose properties depend on binding site arrangement and affinity.
bioRxiv · Mar 25, 2022Biophysics