Reciprocal interaction between IK1 and If in biological pacemakers: A simulation study
Y. Li, K. Wang, Q. Li, J. C. Hancox, H. Zhang
This study uses computational modeling to show that reducing IK1 and increasing If in ventricular myocytes can generate stable pacemaking activity, providing a theoretical basis for engineered biological pacemakers.
bioRxiv · Jul 23, 2020Bioengineering