Structure and dynamics of cholesterol-mediated aquaporin-0 arrays and implications for lipid rafts
P.-L. Chiu, J. D. Orjuela, B. L. de Groot, C. Aponte-Santamaria, T. Walz
This study determines the structure of AQP0 tetramers in sphingomyelin/cholesterol membranes and shows how cholesterol stabilizes their arrangement through hydrophobic interactions and avidity effects.
bioRxiv · May 16, 2023Biophysics