Author

J. Dideriksen

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Biochemistry· 1

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Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Stein· 1 shared F. B. Larsen· 1 shared K. Lindorff-Larsen· 1 shared M. Cagiada· 1 shared R. Hartmann-Petersen· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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1 shared paperBiochemistry

A. Stein

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1 paper

Recent·Most cited

Rare catechol-O-methyltransferase (COMT) missense variants are structurally unstable proteasome targets

F. B. Larsen, M. Cagiada, J. Dideriksen, A. Stein, K. Lindorff-Larsen, R. Hartmann-Petersen

The paper shows two rare COMT missense variants are structurally unstable, leading to proteasomal degradation and reduced enzyme levels, with degradation independent of COMT isoform.

bioRxiv · Jan 3, 2023Biochemistry