Molecular dynamics of the interaction between the ALS/FTD-associated (GGGGCC)n RNA G-quadruplex structure and the three RRM domains of hnRNP H
M. J. Cava, J. B. Billones, J. Galipon
The paper uses molecular docking and dynamics simulations to study how hnRNP H binds to a G-quadruplex RNA structure linked to ALS/FTD, identifying key residues and a novel binding hotspot.
bioRxiv · May 24, 2023 · PreprintNeuroscience