Joint Generation of Protein Sequence and Structure with RoseTTAFold Sequence Space Diffusion
S. L. Lisanza, J. M. Gershon, S. W. K. Tipps, L. Arnoldt, S. Hendel, J. N. Sims, X. Li, D. Baker
ProteinGenerator uses a diffusion model based on RoseTTAFold to generate protein sequences and structures simultaneously, validated for functional properties and structural accuracy.
bioRxiv · May 8, 2023 · PreprintBiochemistry