Tertiary structural motif sequence statistics enable facile prediction and design of peptides that bind anti-apoptotic Bfl-1 and Mcl-1
V. Frappier, J. M. Jenson, J. Zhou, G. Grigoryan, A. E. Keating
This paper introduces a method using tertiary structural motifs to predict and design peptides that bind anti-apoptotic proteins Bfl-1 and Mcl-1 with high accuracy and efficiency.
bioRxiv · Oct 25, 2018Biophysics