Intracellular Cryptococcus neoformans disrupts the transcriptome profile of M1- and M2-polarized host macrophages
A. Subramani, P. Griggs, N. Frantzen, J. Mendez, J. Tucker, J. Murriel, L. Sircy, E. E. McClelland, R. L. Seipelt-Thiemann, D. E. Nelson
This study investigates how Cryptococcus neoformans infection alters gene expression in M1 and M2 polarized macrophages, revealing transcriptome changes resembling naive macrophages and identifying common upregulated genes.
bioRxiv · May 14, 2020Immunology