Author

J. R. Rubin

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Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Organism:human· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

D. Y. Baek· 1 shared E. Schipani· 1 shared E. T. Keller· 1 shared H. Roca· 1 shared L. K. McCauley· 1 shared P. M. Schnepp· 1 shared V. Mendoza-Reinoso· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

D. Y. Baek

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1 paper

Recent·Most cited

Macrophages induce inflammation by efferocytosis of apoptotic prostate cancer cells via HIF-1α stabilization

V. Mendoza-Reinoso, P. M. Schnepp, D. Y. Baek, J. R. Rubin, E. Schipani, E. T. Keller, L. K. McCauley, H. Roca

This study shows that macrophages clear apoptotic prostate cancer cells via efferocytosis, inducing HIF-1α stabilization and MIF expression, which promotes inflammation and tumor growth in bone.

bioRxiv · Sep 2, 2021 · PreprintCancer Biology