Sequence analysis of Indian SARS-CoV-2 isolates shows a stronger interaction of mutated receptor binding domain with ACE2 receptor
P. Dash, J. Turuk, S. K. Behera, S. K. Palo, S. Raghav, A. Ghosh, J. Sabat, S. Rath, S. Subhadra, D. Bhattacharya, S. Kanungo, J. Kshatri, B. k. Mishra, S. Dash, N. Mahapatra, , S. Pati
The study analyzes SARS-CoV-2 isolates from India, finding a mutation in the RBD that increases binding affinity to human ACE2, suggesting potential for higher infectivity and cross-species transmission.
International Journal of Infectious Diseases · Mar 1, 2021Peer-reviewedMicrobiology