Author

J. W. Bruggeman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

G. Hamer· 2 shared A. M. M. van Pelt· 1 shared J. J. B. Koster· 1 shared J. Koster· 1 shared N. Irie· 1 shared P. Lodder· 1 shared S. Repping· 1 shared

Activity by Year

2017-2020 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 13 mutual co-author links

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2 shared papersCancer Biology

G. Hamer

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2 papers

Recent·Most cited

Tumors widely express hundreds of embryonic germline genes

J. W. Bruggeman, N. Irie, P. Lodder, A. M. M. van Pelt, J. Koster, G. Hamer

The paper identifies 672 germ cell cancer genes, expanding the known pool by 51%, and suggests they may offer better cancer treatment targets with fewer side effects.

bioRxiv · Sep 8, 2020Cancer Biology

Massive expression of germ cell specific genes is a hallmark of cancer and a potential target for novel treatment development

J. W. Bruggeman, J. J. B. Koster, S. Repping, G. Hamer

The paper identifies hundreds of true germ cell specific genes expressed in tumors, which could be targeted for cancer therapy with minimal side effects.

bioRxiv · Sep 28, 2017Cancer Biology