Moving from Association to Causation: Instrumental factor models for causal inference in high-dimensional multi-omics data
Aditya Mishra, Michelle H. Badri, Elizabeth Coler, Zhe Liu, Richard Bonneau, James T Morton, Alexander A. Aksenov
This paper introduces FactorIV, a causal inference method for high-dimensional multi-omics data, demonstrating its ability to recover causal effects in biological systems.
bioRxiv · Dec 27, 2025 · PreprintBioinformatics