Rapid Genotype Refinement for Whole-Genome Sequencing Data using Multi-Variate Normal Distributions
Rudy Arthur, Jared O'Connell, Ole Schulz-Trieglaff, Anthony J Cox
The paper introduces a fast genotype refinement method using multivariate normal distributions for whole-genome sequencing data, showing it is hundreds of times faster than existing methods.
bioRxiv · Nov 12, 2015Bioinformatics