Contrastive Representation Learning for Single Cell Phenotyping in Whole Slide Imaging of Enrichment-free Liquid Biopsy
Amin Naghdloo, Dean Tessone, Rajiv M. Nagaraju, Brian Zhang, Jeffrey Kang, Shouyi Li, Assad A. Oberai, James B Hicks, Peter Kühn
This paper introduces a contrastive learning framework for single-cell phenotyping in whole slide imaging of liquid biopsy samples, achieving high accuracy and enabling automated identification of rare cell phenotypes.
bioRxiv · May 21, 2025 · PreprintCancer Biology