Dynamical System Modeling to Simulate Donor T Cell Response to Whole Exome Sequencing-Derived Recipient Peptides Demonstrates Different Alloreactivity Potential In HLA-Matched and Mismatched Donor-Recipient Pairs
Badar Abdul Razzaq, Allison Scalora, Vishal Koparde, Jeremy Meier, Musa Mahmood, Salman Salman, Max Jameson-Lee, Myrna Serrano, Nihar Sheth, Mark Voelkner, David Kobulnicky, Catherine Roberts, Andrea Ferreira-Gonzalez, Masoud Manjili, Gregory Buck, , Amir Toor
This paper simulates donor T cell responses to recipient peptides using exome sequencing data to predict alloreactivity in HLA-matched and mismatched donor-recipient pairs.
bioRxiv · Aug 17, 2015Immunology