Jiaan Dai

Understanding the limit of open search in the identification of peptides with post-translational modifications -- A simulation-based study

The paper evaluates open search methods for identifying modified peptides through simulations and proposes an analytical model to quantify performance based on spectrum quality and PTM count.

Xolik: finding cross-linked peptides with maximum paired scores in linear time

Xolik identifies cross-linked peptides efficiently by reducing computational complexity and outperforms existing tools in speed and statistical power.