KSHV-encoded vIRF3 Cooperates with Cellular IRF4 to Drive Super-Enhancer Activity through Complex DNA Elements
Ziyan Liang, Haocong Katherine Ma, Christine B. Magdongon, Maureen E. Haynes, Jingyi Lu, Elizabeth T. Bartom, Eva Gottwein
This study identifies DNA elements that mediate vIRF3 and IRF4 cooperation in activating super-enhancers, revealing their role in oncogenesis.
Nucleic Acids Research · Sep 18, 2026Peer-reviewedMolecular Biology