Clonal evolution during metastatic spread in high-risk neuroblastoma
Gunes Gundem, Max Fine Levine, Stephen S. Roberts, Irene Y. Cheung, Juan Santiago Medina-Martinez, Yi Feng, Juan Arango Ossa, Loic Chadoutaud, Mathieu Rita, Georgios Asimomitis, Joe Zhou, Daoqi You, Nancy Bouvier, Barbara G. Spitzer, David B. Solit, , Elli Papaemmanuil
This study traces clonal evolution in high-risk neuroblastoma using genomic data from 470 samples, showing metastatic clones can remain dormant and later cause relapses.
Nature Genetics · May 11, 2023Peer-reviewedGenomics