Characterization and Functional Assessment of Epicardial Secretome: Epicardium-Derived Extracellular Vesicles and Matrix
Cláudia C. Oliveira, José Córdoba, John R. Pearson, Elizabeth Guruceaga, Ernesto Marín‐Sedeño, Melissa García‐Caballero, Juan Antonio Guadix, José María Pérez-Pomares, Adrián Ruiz‐Villalba
This study characterizes and functionally assesses epicardial secretome components, showing hypoxic EVs enhance cell proliferation and metabolic responses, while EPIC-ECM promotes endothelial cell growth.
bioRxiv · Nov 29, 2024 · PreprintDevelopmental Biology