Directing Protein Design Choices by Per-Residue Energy Breakdown Analysis with an Interactive Web Application
Felipe Engelberger, Jonathan D. Zakary, Georg Künze
The paper introduces ENDURE, a web tool for analyzing energetic contributions of protein mutations to guide design, showing it improves thermodynamic stability in PET-degrading enzymes.
bioRxiv · Feb 27, 2023 · PreprintBioinformatics