Choosing subsamples for sequencing studies by minimizing the average distance to the closest leaf
Jonathan T. L. Kang, Peng Zhang, Sebastian Zöllner, Noah A. Rosenberg
The paper introduces a method to select internal reference panels for imputation by minimizing average distance to the closest leaf, showing improved accuracy compared to maximizing phylogenetic diversity.
Genetics · Oct 1, 2015Peer-reviewedBioinformatics