MAGMA: Generalized Gene-Set Analysis of GWAS Data
Christiaan de Leeuw, Joris M. Mooij, Tom Heskes, Daniëlle Posthuma
MAGMA couples principal-components regression gene tests with gene-level regression for gene sets, detecting more Crohn's Disease genes and pathways than PLINK while running far faster.
PLoS Computational Biology · Apr 17, 2015Peer-reviewedBioinformatics✦ In-depth digest