Elucidating the crosstalk between inflammation and DNA damage pathways in the pancreatic beta-cell through the diabetes susceptibility gene, TCF19
Grace H. Y. Yang, Danielle A. Fontaine, Sukanya Lodh, Joseph T. Blumer, Avtar Roopra, Dawn Belt Davis
This study investigates the effects of TCF19 overexpression in pancreatic beta-cells, revealing increased DNA damage response and inflammatory gene expression.
bioRxiv · Apr 6, 2021 · PreprintMolecular Biology