A lack of distinct cell identities in single-cell measurements: revisiting Waddingtons landscape
Breanne Sparta, Timothy Hamilton, Juan V. Najar, Serena Hughes, Gunalan Natesan, Eric J. Deeds
This paper challenges the idea that distinct cell types correspond to attractors in gene expression space by showing cells of different types occupy the same regions in epigenetic space.
bioRxiv · Jun 3, 2022 · PreprintSystems Biology