Biologically-informed Interpretable Deep Learning Framework for Phenotype Prediction and Gene Interaction Detection
Chloe Catherine Hequet, Oscar E. Gaggiotti, Silvia Paracchini, Elena G. Bochukova, Juan Ye
This paper introduces GENEPAIR, a DNN interpretation framework for detecting gene-gene interactions in genomic data, demonstrating its ability to uncover both known and novel gene interactions related to BMI.
bioRxiv · Apr 11, 2025 · PreprintGenomics