Glymphatic system health in early Alzheimer's disease and its relationship to sleep, cognition and CSF biomarkers.
Nicola J. Ray, Natàlia Cullell, Oliver James Clark, Ariane Delgado-Sánchez, Giovanni Caruana, Andrea Elias-Mas, Julia Ferrer, Maríateresa Buongiorno, Judith Castejón, Gonzalo Sánchez‐Benavides, Esther Granell, Sônia A. L. Corrêa, Jerzy Krupiński
The paper investigates glymphatic system function in early Alzheimer's disease, finding associations between clearance efficiency, sleep, cognition, and CSF biomarkers, with unexpected relationships between biomarker levels and clearance rates.
bioRxiv · Oct 14, 2024 · PreprintNeuroscience