sCellST: a Multiple Instance Learning approach to predict single-cell gene expression from H&E images using spatial transcriptomics
Loïc Chadoutaud, Marvin Lerousseau, Daniel Herrero-Saboya, Julian Ostermaier, Jacqueline Fontugne, Emmanuel Barillot, Thomas Walter
sCellST predicts single-cell gene expression from H&E images using spatial transcriptomics data, outperforming traditional methods in pancreatic cancer and detecting morphological differences in ovarian cancer.
bioRxiv · Nov 7, 2024 · PreprintBioinformatics