Alfaxalone activates Human Pregnane-X Receptors with greater efficacy than Allopregnanolone: an in-vitro study with implications for neuroprotection during anesthesia.
Juliet M. Serrao, Colin S. Goodchild
This study compares the efficacy of alfaxalone and allopregnanolone in activating human pregnane X receptors using an in vitro assay with HEK293 cells.
bioRxiv · Sep 5, 2020 · PreprintNeuroscience