Proteome-wide structural probing of low-abundant protein interactions by crosslinking
Julius Fürsch, Kai-Michael Kammer, Stefan G. Kreft, Martin Beck, Florian Stengel
This study identifies a bias in proteome-wide crosslinking towards high-abundant proteins and shows how optimizing kinetic parameters can enhance detection of lower-abundant proteins.
Analytical Chemistry · Feb 3, 2020Peer-reviewedSystems Biology