Interparental Gene Conversion in General Population: A Novel Mechanism For Loss of Heterozygosity
Jumpei Toratani, Masahito Tachibana, Junichi Sugawara, Atsushi Sugawara, Takeki Sato, Yuri Takahashi, Hiroaki Hiraga, Emi Yokoyama, Zen Watanabe, Masatoshi Saito, Nobuo Yaegashi, Gen Tamiya, Jun Takayama
The paper identifies interparental gene conversion events in the general population, finding one event per 21.8 births and linking it to loss of heterozygosity and potential genetic disease mechanisms.
bioRxiv · Dec 5, 2024 · PreprintGenomics