GOLDEN: Gene expression and allele-informed decomposition for genetic heterogeneity in spatial transcriptomic data
Sangjeong Lee, Tae Lyun Ko, Hyoung‐Sam Heo, Junguee Lee, Sung Ki Lee, Hyojung Paik
GOLDEN deconvolves genetic heterogeneity in spatial transcriptomic data by integrating gene expression and allele information, achieving high accuracy in fraction estimation and classification.
bioRxiv · Oct 20, 2026 · PreprintBioinformatics