Delicate balances in cancer chemotherapy: modeling immune recruitment and emergence of systemic drug resistance
Anh Phong Tran, M. Ali Al-Radhawi, Irina Kareva, Junjie Wu, David J. Waxman, Eduardo D. Sontag
The paper develops a mathematical model to explain immune recruitment and drug resistance in metronomic chemotherapy using a mouse glioma model and validates it across different drug regimens.
Frontiers in Immunology · Jun 30, 2020Peer-reviewedSystems Biology