Polygenic risk score based on weight gain trajectories is a strong predictor of childhood obesity
Sarah J. C. Craig, Ana M. Kenney, Junli Lin, Ian M. Paul, Leann L. Birch, Jennifer S. Savage, Michele E. Marini, Francesca Chiaromonte, Matthew L. Reimherr, Kateryna D. Makova
This paper develops a polygenic risk score for childhood obesity using longitudinal weight gain data and shows it predicts obesity risk better than adult GWAS-based scores.
bioRxiv · Feb 16, 2020 · PreprintGenetics