Contrastive Fitness Learning: Reprogramming Protein Language Models for Low-N Learning of Protein Fitness Landscape
Junming Zhao, Chao Zhang, Yunan Luo
This paper introduces ConFit, a method to train protein language models with limited experimental data for fitness prediction, showing improved accuracy and efficiency in low-N learning scenarios.
bioRxiv · Feb 11, 2024 · PreprintBioinformatics