Membrane-associated α-tubulin is less acetylated in postmortem prefrontal cortex from depressed subjects relative to controls: cytoskeletal dynamics, HDAC6 and depression
Harinder Singh, Justyna Chmura, Runa Bhaumik, Ghanshyam N. Pandey, Mark M. Rasenick
This study finds that membrane-associated α-tubulin is less acetylated in postmortem prefrontal cortex from depressed subjects compared to controls, suggesting a link between tubulin modification and impaired Gs signaling in depression.
Journal of Neuroscience · Apr 13, 2020Peer-reviewedNeuroscience