AI-driven Deep Visual Proteomics defines cell identity and heterogeneity
Andreas Mund, Fabian Coscia, Réka Hollandi, Ferenc Kovács, András Kriston, Andreas‐David Brunner, Michael Bzorek, Soraya Naimy, Lise Mette Rahbek Gjerdrum, Beatrice Dyring‐Andersen, Jutta Bulkescher, Claudia Lukas, Christian Gnann, Emma K. Lundberg, Péter Horváth, Matthias Mann
Pairing AI-driven image analysis with automated laser microdissection and sensitive mass spectrometry yields proteomes of single cells or nuclei chosen by their morphology, with tissue position retained.
bioRxiv · Jan 25, 2021 · PreprintSystems Biology