White matter hyperintensity genetic risk factor TRIM47 regulates autophagy in brain endothelial cells
S. H.-S. Yeung, R. H.-S. Lee, G. W.-Y. Cheng, I. W.-T. Ma, J. Kofler, C. Kent, F. Ma, K. Herrup, M. Fornage, K. Arai, K.-H. Tse
The paper identifies TRIM47 as a genetic risk factor for white matter hyperintensity and shows it inhibits autophagy in brain endothelial cells.
bioRxiv · Dec 18, 2023Cell Biology