Structural implications of BK polyomavirus sequence variations in the major viral capsid protein Vp1 and large T-antigen: a computational study
J. Durairaj, O. Follonier, K. Leuzinger, L. T. Alexander, M. Wilhelm, J. Pereira, C. A. Hillenbrand, F. Weissbach, T. Schwede, H. H. Hirsch
This study analyzes BKPyV sequence variations in Vp1 and LTag using computational methods, finding high variability in Vp1 that may impact immune control and vaccine design, while LTag shows less variability but potential effects on T-cell epitopes.
bioRxiv · Dec 21, 2023Microbiology