The client-binding domain of the cochaperone SGTA/Sgt2 has a helical-hand structure that binds a short hydrophobic helix
K.-F. Lin, M. Y. Fry, S. Saladi, W. M. Clemons
This study identifies the helical-hand structure of SGTA/Sgt2's client-binding domain and its specificity for hydrophobic TA IMP clients.
bioRxiv · Sep 16, 2020 · PreprintBiochemistry