Phylogenetically estimated neutral rates and fitness effects of mutations to influenza proteins
Hugh K. Haddox, Angie S. Hinrichs, Chris Jennings-Shaffer, Karrington Johnson, Chelsea T Benton, Jared Galloway, Jesse D. Bloom, Frederick A. Matsen IV
The paper estimates neutral mutation rates and fitness effects of mutations in influenza proteins using phylogenetic analysis of over 100,000 sequences, revealing context-dependent patterns across viruses.
bioRxiv · May 20, 2026 · PreprintBioinformatics