Platelet Molecular Maturation Links Platelet Aging and the Platelet Storage Lesion
Cedric M.V. Bainton, Yale A. Santos, Fahima Mayer, Alexander T. Fields, Karl Zoghbi, Nasima Mayer, Danielle Williamson, Greg Chinn, Katelin C. Rahn, Javonn Musgrove, Kimberly A. Thomas, Jeffrey W. Sall, Susan M. Shea, Lucy Zumwinkle Kornblith, Roland J. Bainton
This paper identifies a conserved molecular maturation program in platelets that links aging and storage lesions, showing cold storage preserves transcript stability and hemostatic function.
bioRxiv · Feb 5, 2026 · PreprintGenomics