Improving reporting standards for polygenic scores in risk prediction studies
Hannah Wand, Samuel A. Lambert, Cecelia P. Tamburro, Michael A. Iacocca, Jack William O’Sullivan, Catherine H. Sillari, Iftikhar J. Kullo, Robb K. Rowley, Jacqueline S. Dron, Deanna Brockman, Eric Venner, Mark I. McCarthy, Antonis C. Antoniou, Douglas F. Easton, Robert Alexander Hegele, , Genevieve L. Wojcik
ClinGen and the PGS Catalog expand the GRIPS guideline into a 22-item Polygenic Risk Score Reporting Statement covering study populations, model construction, evaluation, and clinical interpretation.
Nature · Mar 10, 2021Peer-reviewedGenetic & Genomic Medicine✦ In-depth digest