Author
Broad InstituteORCID 0000-0003-3722-0675Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
4 papers
Recent·Most cited
Deanna Brockman, Lia Petronio, Jacqueline S. Dron…·Amit V. Khera
The paper designs and tests a polygenic score report for coronary artery disease, identifying user preferences for visual elements, risk communication, and personalized resources.
Deanna Brockman, Christina Anne Austin-Tse, Renée C. Pelletier…·Miriam S. Udler
This study compares genome sequencing with standard-of-care genetic testing, finding similar diagnostic yields but longer turnaround times for genome sequencing.
Hannah Wand, Samuel A. Lambert, Cecelia P. Tamburro…·Genevieve L. Wojcik
ClinGen and the PGS Catalog expand the GRIPS guideline into a 22-item Polygenic Risk Score Reporting Statement covering study populations, model construction, evaluation, and clinical interpretation.
Akl C. Fahed, Minxian Wang, Julian R. Homburger…·Amit V. Khera
The paper examines how polygenic risk modifies the penetrance of monogenic variants in coronary artery disease, breast cancer, and colorectal cancer across multiple cohorts.