An expanded analysis framework for multivariate GWAS connects inflammatory biomarkers to functional variants and disease
Sanni Ruotsalainen, Juulia Partanen, Anna Cichońska, Jake Lin, Christian Benner, Ida L. Surakka, FinnGen, Aarno Palotie, Mark J. Daly, Pharmaceutical companies, Howard J. Jacob, Athena Matakidou, Heiko Runz, Sally John, Robert M. Plenge, , Kari Linden
The paper introduces a multivariate GWAS framework that identifies functional variants and disease associations by transforming multivariate results into univariate phenotypes for follow-up analysis.
European Journal of Human Genetics · Oct 27, 2020Peer-reviewedGenetics