A post-inflammatory C3-high astrocyte state persists after inflammatory stimulus withdrawal and is attenuated by JAK inhibition
Yogo Sakakibara, Kyohei Okahara, Jungo Kakuta, Kazumi Emoto, Yuri Ofusa, Kenji Ohba
The paper shows that inflammatory stimulation leads to a persistent C3-high astrocyte state after stimulus removal, which is reduced by JAK inhibition.
bioRxiv · May 29, 2026 · PreprintNeuroscience