Myeloid FtH Regulates Macrophage Response to Kidney Injury by Modulating Snca and Ferroptosis
Tanima Chatterjee, Sarah Elizabeth Machado, Kellen A. Cowen, Mary Elizabeth Miller, Yanfeng Zhang, Laura A. Volpicelli‐Daley, Lauren A. Fielding, Rudradip Pattanayak, Frida Rosenblum, László Potor, György Balla, József Balla, Christian Faul, Abolfazl Zarjou
This study shows that myeloid FtH deficiency worsens kidney injury by promoting ferroptosis through Snca and Spic, linking iron trafficking to macrophage dysfunction.
bioRxiv · Mar 25, 2025 · PreprintPathology