Declining RNA integrity in control autopsy brain tissue is robustly and asymmetrically associated with selective neuronal mRNA signal loss
Eleanor S. Johnson, Kendra E. Stenzel, Sangderk Lee, Eric M. Blalock
The paper investigates how RNA integrity numbers (RINs) affect mRNA expression in control autopsy brain tissue, finding pathway-specific and non-linear degradation patterns.
bioRxiv · Sep 7, 2021 · PreprintBioinformatics